2H64
Crystal structure of a ternary ligand-receptor complex of BMP-2
Summary for 2H64
Entry DOI | 10.2210/pdb2h64/pdb |
Related | 1REU 2H62 |
Descriptor | Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA, Acvr2b protein, ... (4 entities in total) |
Functional Keywords | tgf-beta superfamily, ligand-receptor complex, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P12643 Membrane; Single-pass type I membrane protein: P36894 |
Total number of polymer chains | 3 |
Total formula weight | 38789.55 |
Authors | Mueller, T.D.,Sebald, W.,Weber, D. (deposition date: 2006-05-30, release date: 2007-04-10, Last modification date: 2021-10-20) |
Primary citation | Weber, D.,Kotzsch, A.,Nickel, J.,Harth, S.,Seher, A.,Mueller, U.,Sebald, W.,Mueller, T.D. A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor. Bmc Struct.Biol., 7:6-6, 2007 Cited by PubMed: 17295905DOI: 10.1186/1472-6807-7-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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