2GYS

2.7 A structure of the extracellular domains of the human beta common receptor involved in IL-3, IL-5, and GM-CSF signalling

2GYS の概要

• エントリーDOI: 10.2210/pdb2gys/pdb
• 関連するPDBエントリー: 1gh7
• 分子名称: Cytokine receptor common beta chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: dimer of interlocking chains of fibronectin-iii domains, four fibronectin-iii domains per chain, signaling protein, cytokine
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 98231.39

構造登録者

Carr, P.D.,Conlan, F.,Ford, S.,Ollis, D.L.,Young, I.G. (登録日: 2006-05-09, 公開日: 2006-06-20, 最終更新日: 2023-08-30)

• 主引用文献: Carr, P.D.,Conlan, F.,Ford, S.,Ollis, D.L.,Young, I.G.; An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope.; Acta Crystallogr.,Sect.F, 62:509-513, 2006; PubMed: 16754968; DOI: 10.1107/S1744309106016812

実験手法

X-RAY DIFFRACTION (2.7 Å)