2GT4

Crystal Structure of the Y103F mutant of the GDP-mannose mannosyl hydrolase in complex with GDP-mannose and MG+2

Summary for 2GT4

• Entry DOI: 10.2210/pdb2gt4/pdb
• Related: 1RYA 2GT2
• Descriptor: GDP-mannose mannosyl hydrolase, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, ... (5 entities in total)
• Functional Keywords: gdp-mannose hydrolase gdp-glucose hydrolase nudix gdp gdp-fucose, hydrolase
• Biological source: Escherichia coli K12
• Total number of polymer chains: 3
• Total formula weight: 57475.13

Authors

Gabelli, S.B.,Bianchet, M.A.,Azurmendi, H.F.,Mildvan, A.S.,Amzel, L.A. (deposition date: 2006-04-27, release date: 2006-12-12, Last modification date: 2023-08-30)

• Primary citation: Gabelli, S.B.,Azurmendi, H.F.,Bianchet, M.A.,Amzel, L.M.,Mildvan, A.S.; X-ray, NMR, and mutational studies of the catalytic cycle of the GDP-mannose mannosyl hydrolase reaction.; Biochemistry, 45:11290-11303, 2006; PubMed: 16981689; DOI: 10.1021/bi061239g

Experimental method

X-RAY DIFFRACTION (2.3 Å)