2GJ6

The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide

2GJ6 の概要

• エントリーDOI: 10.2210/pdb2gj6/pdb
• 関連するPDBエントリー: 1AO7 1DUZ 1QRN 1QSE 1QSF 2GIT
• 分子名称: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Contains: Beta-2-microglobulin variant pI 5.3, Modified HTLV-1 TAX (Y5K-IBA) peptide, chain C, ... (9 entities in total)
• 機能のキーワード: htlv-1 tax peptide, haptenated peptide, lysine-4-(3-indolyl)-butyric acid, mhc class i, hla-a2, t-cell receptor a6, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 96099.16

構造登録者

Borbulevych, O.Y.,Baker, B.M. (登録日: 2006-03-30, 公開日: 2006-10-03, 最終更新日: 2023-08-30)

• 主引用文献: Gagnon, S.J.,Borbulevych, O.Y.,Davis-Harrison, R.L.,Turner, R.V.,Damirjian, M.,Wojnarowicz, A.,Biddison, W.E.,Baker, B.M.; T Cell Receptor Recognition via Cooperative Conformational Plasticity.; J.Mol.Biol., 363:228-243, 2006; PubMed: 16962135; DOI: 10.1016/j.jmb.2006.08.045

実験手法

X-RAY DIFFRACTION (2.56 Å)