2GJ6
The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, A-2 alpha chain | polymer | 275 | 31854.2 | 1 | UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) | Homo sapiens (human) | MHC class I antigen A*2 |
| 2 | B (B) | Beta-2-microglobulin, Contains: Beta-2-microglobulin variant pI 5.3 | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | Modified HTLV-1 TAX (Y5K-IBA) peptide, chain C | polymer | 9 | 1036.3 | 1 | |||
| 4 | D (D) | A6-Tcr | polymer | 200 | 22088.2 | 1 | GenBank (6730548) Pfam (PF09291) UniProt (by SIFTS) (P01848) | Homo sapiens (human) | |
| 5 | E (E) | A6-Tcr | polymer | 245 | 27360.4 | 1 | GenBank (6730544) Pfam (PF07654) UniProt (by SIFTS) (P01850) | Homo sapiens (human) | |
| 6 | F, G, J, U, V (A, B, E) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 7 | H, I, K, L, M... (A, B, C, E) | GLYCEROL | non-polymer | 92.1 | 13 | Chemie (GOL) | |||
| 8 | S (C) | 3-INDOLEBUTYRIC ACID | non-polymer | 203.2 | 1 | Chemie (3IB) | |||
| 9 | AA, BA, CA, Y, Z (C, D, E, A, B) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
B: 1 - 99 (UniProt: P61769)
E: 3 - 245 (GenBank: 6730544)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Asn 1 | - | cloning artifact |
| Ala 2 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 94218.4 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1880.8 | |
| All* | Total formula weight | 96099.2 |
