2GJ4

Structure of rabbit muscle glycogen phosphorylase in complex with ligand

Summary for 2GJ4

DescriptorGlycogen phosphorylase, muscle form, SULFATE ION, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ... (5 entities in total)
Functional Keywordsglycogen phosphorylase, transferase
Biological sourceOryctolagus cuniculus (rabbit)
Total number of polymer chains1
Total molecular weight96544.3
Authors
Otterbein, L.R.,Pannifer, A.D.,Tucker, J.,Breed, J.,Oikonomakos, N.G.,Rowsell, S.,Pauptit, R.A.,Claire, M. (deposition date: 2006-03-30, release date: 2007-02-13, Last modification date: 2011-07-13)
Primary citation
Whittamore, P.R.,Addie, M.S.,Bennett, S.N.,Birch, A.M.,Butters, M.,Godfrey, L.,Kenny, P.W.,Morley, A.D.,Murray, P.M.,Oikonomakos, N.G.,Otterbein, L.R.,Pannifer, A.D.,Parker, J.S.,Readman, K.,Siedlecki, P.S.,Schofield, P.,Stocker, A.,Taylor, M.J.,Townsend, L.A.,Whalley, D.P.,Whitehouse, J.
Novel thienopyrrole glycogen phosphorylase inhibitors: synthesis, in vitro SAR and crystallographic studies.
Bioorg.Med.Chem.Lett., 16:5567-5571, 2006
PubMed: 16945526 (PDB entries with the same primary citation)
DOI: 10.1016/j.bmcl.2006.08.047
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.228202.4%2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution