2GIF
Asymmetric structure of trimeric AcrB from Escherichia coli
Summary for 2GIF
Entry DOI | 10.2210/pdb2gif/pdb |
Related | 1IWG |
Descriptor | Acriflavine resistance protein B, CITRATE ANION (2 entities in total) |
Functional Keywords | membrane protein, secondary transport, rnd, antibiotic resistance, drug-efflux pump, alternating site mechanism, membrane protein-transport protein complex, membrane protein/transport protein |
Biological source | Escherichia coli |
Cellular location | Cell inner membrane ; Multi- pass membrane protein : P31224 |
Total number of polymer chains | 3 |
Total formula weight | 344587.07 |
Authors | Seeger, M.A.,Schiefner, A.,Eicher, T.,Verrey, F.,Diederichs, K.,Pos, K.M. (deposition date: 2006-03-28, release date: 2006-09-12, Last modification date: 2023-08-30) |
Primary citation | Seeger, M.A.,Schiefner, A.,Eicher, T.,Verrey, F.,Diederichs, K.,Pos, K.M. Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism. Science, 313:1295-1298, 2006 Cited by PubMed: 16946072DOI: 10.1126/science.1131542 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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