2GGV
Crystal structure of the West Nile virus NS2B-NS3 protease, His51Ala mutant
Summary for 2GGV
Entry DOI | 10.2210/pdb2ggv/pdb |
Descriptor | non-structural protein 2B, non-structural protein 3 (3 entities in total) |
Functional Keywords | beta barrel, serine protease, viral protease, flavivirus, hydrolase |
Biological source | West Nile virus More |
Cellular location | Envelope protein E: Virion membrane; Multi- pass membrane protein: Q203W3 Q203W3 |
Total number of polymer chains | 2 |
Total formula weight | 26016.94 |
Authors | Aleshin, A.E.,Shiryaev, S.A.,Strongin, A.Y.,Liddington, R.C. (deposition date: 2006-03-24, release date: 2007-03-27, Last modification date: 2024-02-14) |
Primary citation | Aleshin, A.E.,Shiryaev, S.A.,Strongin, A.Y.,Liddington, R.C. Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold. Protein Sci., 16:795-806, 2007 Cited by PubMed: 17400917DOI: 10.1110/ps.072753207 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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