2GEB
Crystal structure of the Thermoanaerobacter tengcongensis hypoxanthine-guanine phosphoribosyltransferase L160I mutant: insights into the inhibitor design
Summary for 2GEB
Entry DOI | 10.2210/pdb2geb/pdb |
Related | 1R3U 1YFZ |
Descriptor | Hypoxanthine-guanine phosphoribosyltransferase, CALCIUM ION (3 entities in total) |
Functional Keywords | hgprt, mutant, inhibitor design, selectivity, transferase |
Biological source | Thermoanaerobacter tengcongensis |
Total number of polymer chains | 1 |
Total formula weight | 20849.40 |
Authors | |
Primary citation | Chen, Q.,You, D.,Liang, Y.,Su, X.,Gu, X.,Luo, M.,Zheng, X. Crystal structure of Thermoanaerobacter tengcongensis hypoxanthine-guanine phosphoribosyl transferase L160I mutant--insights into inhibitor design. Febs J., 274:4408-4415, 2007 Cited by PubMed: 17662107DOI: 10.1111/j.1742-4658.2007.05970.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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