2GCO

Crystal structure of the human RhoC-GppNHp complex

Summary for 2GCO

Related2GCN 2GCP
DescriptorRho-related GTP-binding protein RhoC, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (5 entities in total)
Functional Keywordsgtp-binding protein, gtpase, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor; Cytoplasmic side (Potential) P08134 P08134
Total number of polymer chains2
Total molecular weight46558.79
Authors
Dias, S.M.G.,Cerione, R.A. (deposition date: 2006-03-14, release date: 2007-03-27, Last modification date: 2011-07-13)
Primary citation
Dias, S.M.G.,Cerione, R.A.
X-ray Crystal Structures Reveal Two Activated States for RhoC.
Biochemistry, 46:6547-6558, 2007
PubMed: 17497936 (PDB entries with the same primary citation)
DOI: 10.1021/bi700035p
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21530.3%1.2%6.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2gco
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Molmil generated image of 2gco
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Molmil generated image of 2gco
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More Biological unit images

Molmil generated image of 2gco
no rotation
Molmil generated image of 2gco
rotated about x axis by 90°
Molmil generated image of 2gco
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2gco.pdb2.gz [36.54 KB])
Coordinate files for Biological unit (2gco.pdb1.gz [38.87 KB])