2G3W

The Crystal Structure of YaeQ Protein from Xanthomonas axonopodis pv. citri

Summary for 2G3W

• Entry DOI: 10.2210/pdb2g3w/pdb
• Descriptor: hypothetical protein XAC2396, ACETATE ION (3 entities in total)
• Functional Keywords: yaeq protein, xanthomonas axonopodis pv citri, unknown function
• Biological source: Xanthomonas axonopodis pv. citri
• Total number of polymer chains: 2
• Total formula weight: 42097.01

Authors

Farah, C.S.,Guzzo, C.R.,Barbosa, J.A.R.G.,Nagem, R.A.P. (deposition date: 2006-02-21, release date: 2007-02-27, Last modification date: 2024-11-06)

Primary citation

Guzzo, C.R.,Nagem, R.A.P.,Barbosa, J.A.R.G.,Farah, C.S.
Structure of Xanthomonas axonopodis pv. citri YaeQ reveals a new compact protein fold built around a variation of the PD-(D/E)XK nuclease motif
Proteins, 69:644-651, 2007

PubMed Abstract: The YaeQ family of proteins are found in many Gram-negative and a few Gram-positive bacteria. We have determined the first structure of a member of the YaeQ family by X-ray crystallography. Comparisons with other structures indicate that YaeQ represents a new compact protein fold built around a variation of the PD-(D/E)XK nuclease motif found in type II endonucleases and enzymes involved in DNA replication, repair, and recombination. We show that catalytically important residues in the PD-(D/E)XK nuclease superfamily are spatially conserved in YaeQ and other highly conserved YaeQ residues may be poised to interact with nucleic acid structures.

PubMed: 17623842
DOI: 10.1002/prot.21556

Experimental method

X-RAY DIFFRACTION (1.9 Å)