2FWW

human beta-tryptase II complexed with 4-piperidinebutyrate to make acylenzyme

Summary for 2FWW

Entry DOI	10.2210/pdb2fww/pdb
Related	2FX4 2FX6
Descriptor	Tryptase beta-2, 4-PIPERIDINEBUTYRATE (3 entities in total)
Functional Keywords	serine protease, proteinase, 29382, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Secreted: P20231
Total number of polymer chains	4
Total formula weight	110586.65
Authors	Katz, B.A. (deposition date: 2006-02-03, release date: 2006-02-14, Last modification date: 2017-10-18)
Primary citation	McGrath, M.E.,Sprengeler, P.A.,Hirschbein, B.,Somoza, J.R.,Lehoux, I.,Janc, J.W.,Gjerstad, E.,Graupe, M.,Estiarte, A.,Venkataramani, C.,Liu, Y.,Yee, R.,Ho, J.D.,Green, M.J.,Lee, C.-S.,Liu, L.,Tai, V.,Spencer, J.,Sperandio, D.,Katz, B.A. Structure-guided design of Peptide-based tryptase inhibitors. Biochemistry, 45:5964-5973, 2006 Cited by PubMed: 16681368 DOI: 10.1021/bi060173m PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation