2FX4
Bovine trypsin bound by 4-piperidinebutyrate to make acylenzyme complex
Summary for 2FX4
Entry DOI | 10.2210/pdb2fx4/pdb |
Related | 2FWW 2FX6 |
Descriptor | trypsin, CALCIUM ION, 4-PIPERIDINEBUTYRATE, ... (4 entities in total) |
Functional Keywords | serine protease, acylenzyme complex, hydrolase |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 23519.60 |
Authors | Katz, B.A. (deposition date: 2006-02-03, release date: 2006-02-14, Last modification date: 2017-10-18) |
Primary citation | McGrath, M.E.,Sprengeler, P.A.,Hirschbein, B.,Somoza, J.R.,Lehoux, I.,Janc, J.W.,Gjerstad, E.,Graupe, M.,Estiarte, A.,Venkataramani, C.,Liu, Y.,Yee, R.,Ho, J.D.,Green, M.J.,Lee, C.-S.,Liu, L.,Tai, V.,Spencer, J.,Sperandio, D.,Katz, B.A. Structure-guided design of Peptide-based tryptase inhibitors. Biochemistry, 45:5964-5973, 2006 Cited by PubMed: 16681368DOI: 10.1021/bi060173m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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