2FW4

Carbonic anhydrase activators. The first X-ray crystallographic study of an activator of isoform I, structure with L-histidine.

Summary for 2FW4

Entry DOI	10.2210/pdb2fw4/pdb
Descriptor	Carbonic anhydrase 1, ZINC ION, HISTIDINE, ... (4 entities in total)
Functional Keywords	carbonic anhydrase i, activators, lyase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P00915
Total number of polymer chains	2
Total formula weight	57993.12
Authors	Temperini, C.,Scozzafava, A.,Supuran, C.T. (deposition date: 2006-02-01, release date: 2006-08-08, Last modification date: 2024-02-14)
Primary citation	Temperini, C.,Scozzafava, A.,Supuran, C.T. Carbonic anhydrase activators: The first X-ray crystallographic study of an adduct of isoform I. Bioorg.Med.Chem.Lett., 16:5152-5156, 2006 Cited by PubMed: 16870440 DOI: 10.1016/j.bmcl.2006.07.021 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation