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2FW4

Carbonic anhydrase activators. The first X-ray crystallographic study of an activator of isoform I, structure with L-histidine.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Carbonic anhydrase 1polymer26028775.02UniProt (P00915)
Pfam (PF00194)
Homo sapiens (human)Carbonic anhydrase I, Carbonate dehydratase I, CA-I
2C, E
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
3D, F
(A, B)
HISTIDINEnon-polymer156.22Chemie (HIS)
4G, H
(A, B)
waterwater18.0370Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight57550.0
Non-Polymers*Number of molecules4
Total formula weight443.1
All*Total formula weight57993.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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