2FMO
Ala177Val mutant of E. coli Methylenetetrahydrofolate Reductase
Summary for 2FMO
Entry DOI | 10.2210/pdb2fmo/pdb |
Related | 2FMN |
Descriptor | 5,10-methylenetetrahydrofolate reductase, SULFATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | oxidoreductase, tim barrel, flavin, reductase |
Biological source | Escherichia coli |
Total number of polymer chains | 3 |
Total formula weight | 105923.19 |
Authors | Pejchal, R.,Campbell, E.,Guenther, B.D.,Lennon, B.W.,Matthews, R.G.,Ludwig, M.L. (deposition date: 2006-01-09, release date: 2006-04-25, Last modification date: 2023-08-30) |
Primary citation | Pejchal, R.,Campbell, E.,Guenther, B.D.,Lennon, B.W.,Matthews, R.G.,Ludwig, M.L. Structural Perturbations in the Ala -> Val Polymorphism of Methylenetetrahydrofolate Reductase: How Binding of Folates May Protect against Inactivation Biochemistry, 45:4808-4818, 2006 Cited by PubMed: 16605249DOI: 10.1021/bi052294c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
Download full validation report