2FLD
I-MsoI Re-Designed for Altered DNA Cleavage Specificity
Summary for 2FLD
Entry DOI | 10.2210/pdb2fld/pdb |
Related | 1M5X |
Descriptor | 5'-D(*GP*CP*AP*GP*AP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*CP*GP*TP*TP*CP*CP*G)-3', 5'-D(*CP*GP*GP*AP*AP*CP*GP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*CP*TP*TP*CP*TP*GP*C)-3', DNA ENDONUCLEASE I-MSOI, ... (6 entities in total) |
Functional Keywords | homing endonuclease, dna, hydrolase-dna complex, hydrolase/dna |
Biological source | Monomastix sp. |
Total number of polymer chains | 4 |
Total formula weight | 52715.23 |
Authors | Ashworth, J.,Duarte, C.M.,Havranek, J.J.,Sussman, D.,Monnat, R.J.,Stoddard, B.L.,Baker, D. (deposition date: 2006-01-05, release date: 2006-06-06, Last modification date: 2023-08-30) |
Primary citation | Ashworth, J.,Havranek, J.J.,Duarte, C.M.,Sussman, D.,Monnat, R.J.,Stoddard, B.L.,Baker, D. Computational redesign of endonuclease DNA binding and cleavage specificity. Nature, 441:656-659, 2006 Cited by PubMed: 16738662DOI: 10.1038/nature04818 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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