2FFV

Human ppGalNAcT-2 complexed with manganese and UDP

Summary for 2FFV

Entry DOI	10.2210/pdb2ffv/pdb
Descriptor	Polypeptide N-acetylgalactosaminyltransferase 2, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywords	ppgalnact; mucin; glycosyltransferase, transferase
Biological source	Homo sapiens (human)
Cellular location	Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: Q10471
Total number of polymer chains	2
Total formula weight	115177.89
Authors	Fritz, T.A. (deposition date: 2005-12-20, release date: 2006-01-31, Last modification date: 2023-08-30)
Primary citation	Fritz, T.A.,Raman, J.,Tabak, L.A. Dynamic Association between the Catalytic and Lectin Domains of Human UDP-GalNAc:Polypeptide {alpha}-N-Acetylgalactosaminyltransferase-2 J.Biol.Chem., 281:8613-8619, 2006 Cited by PubMed: 16434399 DOI: 10.1074/jbc.M513590200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation