Crystal Structure of AlkB in complex with Fe(II), 2-oxoglutarate, and methylated trinucleotide T-meA-T

Summary for 2FD8

Related2fdf 2fdg 2fdh 2fdi 2fdj 2fdk
Descriptor5'-D(P*TP*(MA7)P*T)-3', Alkylated DNA repair protein alkB, FE (II) ION, ... (5 entities in total)
Functional Keywordsbeta jellyroll, structural genomics, psi, protein structure initiative, northeast structural genomics consortium, nesg, oxidoreductase-dna complex, oxidoreductase/dna
Biological sourceEscherichia coli K12
Total number of polymer chains2
Total molecular weight24704.59
Yu, B.,Benach, J.,Edstrom, W.C.,Gibney, B.R.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2005-12-13, release date: 2006-02-21, Last modification date: 2017-10-18)
Primary citation
Yu, B.,Edstrom, W.C.,Benach, J.,Hamuro, Y.,Weber, P.C.,Gibney, B.R.,Hunt, J.F.
Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB.
Nature, 439:879-884, 2006
PubMed: 16482161 (PDB entries with the same primary citation)
DOI: 10.1038/nature04561
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2253 0.5% 3.1% 4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-14