2FBW
Avian respiratory complex II with carboxin bound
Summary for 2FBW
Entry DOI | 10.2210/pdb2fbw/pdb |
Related | 1NEK 1QJD 1YQ3 1YQ4 1ZOY 1ZPO 2H88 |
Descriptor | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, ... (19 entities in total) |
Functional Keywords | complex ii, membrane protein, heme protein, iron sulfur protein, cytochrome b, oxidoreductase, redox enzyme, respiratory chain, oxaloacetate nitropropionate ubiquinone |
Biological source | Gallus gallus (Chicken) More |
Total number of polymer chains | 8 |
Total formula weight | 253554.22 |
Authors | Huang, L.S.,Sun, G.,Cobessi, D.,Wang, A.C.,Shen, J.T.,Tung, E.Y.,Anderson, V.E.,Berry, E.A. (deposition date: 2005-12-10, release date: 2005-12-20, Last modification date: 2023-08-30) |
Primary citation | Huang, L.S.,Sun, G.,Cobessi, D.,Wang, A.C.,Shen, J.T.,Tung, E.Y.,Anderson, V.E.,Berry, E.A. 3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme. J.Biol.Chem., 281:5965-5972, 2006 Cited by PubMed: 16371358DOI: 10.1074/jbc.M511270200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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