2FBW

Avian respiratory complex II with carboxin bound

Summary for 2FBW

Entry DOI	10.2210/pdb2fbw/pdb
Related	1NEK 1QJD 1YQ3 1YQ4 1ZOY 1ZPO 2H88
Descriptor	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, ... (19 entities in total)
Functional Keywords	complex ii, membrane protein, heme protein, iron sulfur protein, cytochrome b, oxidoreductase, redox enzyme, respiratory chain, oxaloacetate nitropropionate ubiquinone
Biological source	Gallus gallus (Chicken) More
Total number of polymer chains	8
Total formula weight	253554.22
Authors	Huang, L.S.,Sun, G.,Cobessi, D.,Wang, A.C.,Shen, J.T.,Tung, E.Y.,Anderson, V.E.,Berry, E.A. (deposition date: 2005-12-10, release date: 2005-12-20, Last modification date: 2023-08-30)
Primary citation	Huang, L.S.,Sun, G.,Cobessi, D.,Wang, A.C.,Shen, J.T.,Tung, E.Y.,Anderson, V.E.,Berry, E.A. 3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme. J.Biol.Chem., 281:5965-5972, 2006 Cited by PubMed: 16371358 DOI: 10.1074/jbc.M511270200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.06 Å)

Structure validation