2EZ7
Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII and XIV with L- and D-histidine and crystallographic analysis of their adducts with isoform II: engineering proton transfer processes within the active site of an enzyme
Summary for 2EZ7
Entry DOI | 10.2210/pdb2ez7/pdb |
Descriptor | Carbonic anhydrase 2, MERCURY (II) ION, ZINC ION, ... (5 entities in total) |
Functional Keywords | carbonic anhydrase ii, activators, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29711.22 |
Authors | Temperini, C.,Scozzafava, A.,Vullo, D.,Supuran, C.T. (deposition date: 2005-11-10, release date: 2006-07-18, Last modification date: 2024-02-14) |
Primary citation | Temperini, C.,Scozzafava, A.,Vullo, D.,Supuran, C.T. Carbonic Anhydrase Activators. Activation of Isozymes I, II, IV, VA, VII, and XIV with L- and D-Histidine and Crystallographic Analysis of Their Adducts with Isoform II: Engineering Proton-Transfer Processes within the Active Site of an Enzyme. Chemistry, 12:7057-7066, 2006 Cited by PubMed: 16807956DOI: 10.1002/chem.200600159 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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