2EUF

X-ray structure of human CDK6-Vcyclin in complex with the inhibitor PD0332991

2EUF の概要

• エントリーDOI: 10.2210/pdb2euf/pdb
• 分子名称: viral Cyclin, Cell division protein kinase 6, CALCIUM ION, ... (7 entities in total)
• 機能のキーワード: inhibitor complex of human cyclin-dependent kinase 6, cell cycle-transferase complex, cell cycle/transferase
• 由来する生物種: Herpesvirus saimiri (strain 11); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 64356.54

構造登録者

Schulze-Gahmen, U.,Lu, H. (登録日: 2005-10-28, 公開日: 2006-07-04, 最終更新日: 2024-02-14)

• 主引用文献: Lu, H.,Schulze-Gahmen, U.; Toward understanding the structural basis of cyclin-dependent kinase 6 specific inhibition.; J.Med.Chem., 49:3826-3831, 2006; PubMed: 16789739; DOI: 10.1021/jm0600388

実験手法

X-RAY DIFFRACTION (3 Å)