2EAU
Crystal structure of the SR CA2+-ATPASE with bound CPA in the presence of curcumin
Summary for 2EAU
Entry DOI | 10.2210/pdb2eau/pdb |
Related | 1WPG 2AGV 2EAR 2EAS 2EAT |
Descriptor | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, PHOSPHATIDYLETHANOLAMINE (3 entities in total) |
Functional Keywords | membrane protein, p-type atpase, had fold, ca2+, ion pump, hydrolase |
Biological source | Oryctolagus cuniculus (rabbit) |
Cellular location | Endoplasmic reticulum membrane; Multi-pass membrane protein: P04191 |
Total number of polymer chains | 1 |
Total formula weight | 112167.12 |
Authors | Takahashi, M.,Kondou, Y.,Toyoshima, C. (deposition date: 2007-02-02, release date: 2007-03-27, Last modification date: 2023-10-25) |
Primary citation | Takahashi, M.,Kondou, Y.,Toyoshima, C. Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors Proc.Natl.Acad.Sci.Usa, 104:5800-5805, 2007 Cited by PubMed: 17389383DOI: 10.1073/pnas.0700979104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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