2E8A

Crystal structure of the human Hsp70 ATPase domain in complex with AMP-PNP

2E8A の概要

• エントリーDOI: 10.2210/pdb2e8a/pdb
• 関連するPDBエントリー: 2E88
• 分子名称: Heat shock 70kDa protein 1A, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
• 機能のキーワード: hydrolase, anp, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43624.21

構造登録者

Shida, M.,Ishii, R.,Takagi, T.,Kishishita, S.,Shirouzu, M.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2007-01-19, 公開日: 2008-01-22, 最終更新日: 2023-10-25)

• 主引用文献: Shida, M.,Arakawa, A.,Ishii, R.,Kishishita, S.,Takagi, T.,Kukimoto-Niino, M.,Sugano, S.,Tanaka, A.,Shirouzu, M.,Yokoyama, S.; Direct inter-subdomain interactions switch between the closed and open forms of the Hsp70 nucleotide-binding domain in the nucleotide-free state.; Acta Crystallogr.,Sect.D, 66:223-232, 2010; PubMed: 20179333; DOI: 10.1107/S0907444909053979

実験手法

X-RAY DIFFRACTION (1.77 Å)