2E7F
5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase complexed with methyltetrahydrofolate to 2.2 Angsrom resolution
Summary for 2E7F
Entry DOI | 10.2210/pdb2e7f/pdb |
Related | 1AD4 1AJ0 1F6Y 1Q8J 1TWW 1TX0 |
Descriptor | 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION, 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, ... (4 entities in total) |
Functional Keywords | methyltetrahydrofolate-protein complex, corrionoid, vitamin b12, tim barrel, transferase |
Biological source | Moorella thermoacetica |
Total number of polymer chains | 2 |
Total formula weight | 58275.31 |
Authors | Doukov, T.I.,Drennan, C.L.,Hemmi, H.,Ragsdale, S.W. (deposition date: 2007-01-09, release date: 2007-01-30, Last modification date: 2023-10-25) |
Primary citation | Doukov, T.I.,Hemmi, H.,Drennan, C.L.,Ragsdale, S.W. Structural and kinetic evidence for an extended hydrogen-bonding network in catalysis of methyl group transfer. Role of an active site asparagine residue in activation of methyl transfer by methyltransferases. J.Biol.Chem., 282:6609-6618, 2007 Cited by PubMed: 17172470DOI: 10.1074/jbc.M609828200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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