2E41
Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii Complexed with the Reaction Product Analog Biotinol-5'-AMP, Mutations R48A and K111A
Summary for 2E41
Entry DOI | 10.2210/pdb2e41/pdb |
Related | 1WQW 2E3Y |
Descriptor | biotin--[acetyl-CoA-carboxylase] ligase, ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE (3 entities in total) |
Functional Keywords | biotin biosynthesis, dimer, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, ligase |
Biological source | Pyrococcus horikoshii |
Total number of polymer chains | 2 |
Total formula weight | 53037.68 |
Authors | Bagautdinov, B.,Matsuura, Y.,Bagautdinova, S.,Kunishima, N.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2006-12-01, release date: 2007-06-05, Last modification date: 2023-10-25) |
Primary citation | Bagautdinov, B.,Matsuura, Y.,Bagautdinova, S.,Kunishima, N. Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate J.Biol.Chem., 283:14739-14750, 2008 Cited by PubMed: 18372281DOI: 10.1074/jbc.M709116200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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