2E0A

Crystal structure of human pyruvate dehydrogenase kinase 4 in complex with AMPPNP

2E0A の概要

• エントリーDOI: 10.2210/pdb2e0a/pdb
• 分子名称: Pyruvate dehydrogenase kinase isozyme 4, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
• 機能のキーワード: pdk4, kinase, atp-binding, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion matrix: Q16654
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 90602.99

構造登録者

Kukimoto-Niino, M.,Tokmakov, A.,Terada, T.,Shiromizu, I.,Kawamoto, M.,Matsusue, T.,Shirouzu, M.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2006-10-03, 公開日: 2007-10-09, 最終更新日: 2023-10-25)

• 主引用文献: Kukimoto-Niino, M.,Tokmakov, A.,Terada, T.,Ohbayashi, N.,Fujimoto, T.,Gomi, S.,Shiromizu, I.,Kawamoto, M.,Matsusue, T.,Shirouzu, M.,Yokoyama, S.; Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4.; Acta Crystallogr.,Sect.D, 67:763-773, 2011; PubMed: 21904029; DOI: 10.1107/S090744491102405X

実験手法

X-RAY DIFFRACTION (1.86 Å)