2DHN
COMPLEX OF 7,8-DIHYDRONEOPTERIN ALDOLASE FROM STAPHYLOCOCCUS AUREUS WITH 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 2.2 A RESOLUTION
Summary for 2DHN
Entry DOI | 10.2210/pdb2dhn/pdb |
Descriptor | 7,8-DIHYDRONEOPTERIN ALDOLASE, 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE (3 entities in total) |
Functional Keywords | product complex, pterine binding, folate biosynthesis, antibiotic target, beta-barrel |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 1 |
Total formula weight | 13964.81 |
Authors | Hennig, M.,D'Arcy, A.,Hampele, I.C.,Page, M.G.P.,Oefner, C.H.,Dale, G. (deposition date: 1998-03-31, release date: 1999-04-20, Last modification date: 2024-04-03) |
Primary citation | Hennig, M.,D'Arcy, A.,Hampele, I.C.,Page, M.G.,Oefner, C.,Dale, G.E. Crystal structure and reaction mechanism of 7,8-dihydroneopterin aldolase from Staphylococcus aureus. Nat.Struct.Biol., 5:357-362, 1998 Cited by PubMed: 9586996DOI: 10.1038/nsb0598-357 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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