2D5V

Crystal structure of HNF-6alpha DNA-binding domain in complex with the TTR promoter

Summary for 2D5V

• Entry DOI: 10.2210/pdb2d5v/pdb
• Descriptor: 5'-D(*TP*CP*TP*AP*AP*GP*TP*CP*AP*AP*TP*AP*AP*T)-3', 5'-D(*AP*TP*TP*AP*TP*TP*GP*AP*CP*TP*TP*AP*GP*A)-3', Hepatocyte nuclear factor 6, ... (6 entities in total)
• Functional Keywords: transcription factor, transcription-dna complex, transcription/dna
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Nucleus: P70512
• Total number of polymer chains: 6
• Total formula weight: 56743.09

Authors

Iyaguchi, D.,Yao, M.,Watanabe, N.,Nishihira, J.,Tanaka, I. (deposition date: 2005-11-07, release date: 2006-12-05, Last modification date: 2024-03-13)

• Primary citation: Iyaguchi, D.,Yao, M.,Watanabe, N.,Nishihira, J.,Tanaka, I.; DNA recognition mechanism of the ONECUT homeodomain of transcription factor HNF-6; Structure, 15:75-83, 2007; PubMed: 17223534; DOI: 10.1016/j.str.2006.11.004

Experimental method

X-RAY DIFFRACTION (2 Å)