2D5V
Crystal structure of HNF-6alpha DNA-binding domain in complex with the TTR promoter
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, E | 5'-D(*TP*CP*TP*AP*AP*GP*TP*CP*AP*AP*TP*AP*AP*T)-3' | polymer | 14 | 4262.8 | 2 | |||
2 | D, F | 5'-D(*AP*TP*TP*AP*TP*TP*GP*AP*CP*TP*TP*AP*GP*A)-3' | polymer | 14 | 4293.8 | 2 | |||
3 | A, B | Hepatocyte nuclear factor 6 | polymer | 164 | 19663.8 | 2 | UniProt (P70512) Pfam (PF02376) Pfam (PF00046) In PDB | Rattus norvegicus (Norway rat) | HNF-6, One cut domain family member 1 |
4 | D, E | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
5 | B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
6 | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 156 (UniProt: P70512)
PDB | External Database | Details |
---|---|---|
Leu 157 | - | expression tag |
Glu 158 | - | expression tag |
His 159 | - | expression tag |
His 160 | - | expression tag |
His 161 | - | expression tag |
His 162 | - | expression tag |
His 163 | - | expression tag |
His 164 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 56440.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 302.3 | |
All* | Total formula weight | 56743.1 |