2D4H
Crystal-structure of the N-terminal large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GMP
Summary for 2D4H
| Entry DOI | 10.2210/pdb2d4h/pdb |
| Related | 1DG3 1F5N 2B8W 2B92 |
| Descriptor | Interferon-induced guanylate-binding protein 1, GUANOSINE-5'-MONOPHOSPHATE (3 entities in total) |
| Functional Keywords | protein- guanine nucleotide complex, signaling protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm : P32455 |
| Total number of polymer chains | 2 |
| Total formula weight | 74883.34 |
| Authors | Ghosh, A.,Praefcke, G.J.K.,Renault, L.,Wittinghofer, A.,Herrmann, C. (deposition date: 2005-10-19, release date: 2006-03-07, Last modification date: 2023-08-23) |
| Primary citation | Ghosh, A.,Praefcke, G.J.,Renault, L.,Wittinghofer, A.,Herrmann, C. How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP. Nature, 440:101-104, 2006 Cited by PubMed: 16511497DOI: 10.1038/nature04510 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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