Summary for 2JAV
Entry DOI | 10.2210/pdb2jav/pdb |
Related | 2CL1 |
Descriptor | SERINE/THREONINE-PROTEIN KINASE NEK2, 5-[(Z)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE (3 entities in total) |
Functional Keywords | transferase, phosphorylation, nucleotide-binding, atp-binding, cell division, metal-binding, nuclear protein, serine/threonine-protein kinase, serine/threonine protein kinase, kinase, meiosis, mitosis, magnesium, cell cycle |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 32962.23 |
Authors | Pike, A.C.W.,Rellos, P.,Das, S.,Fedorov, O.,Papagrigoriou, E.,Debreczeni, J.E.,Turnbull, A.P.,Gorrec, F.,Bray, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.,Weigelt, J.,von Delft, F.,Knapp, S. (deposition date: 2006-11-30, release date: 2006-12-04, Last modification date: 2023-12-13) |
Primary citation | Rellos, P.,Ivins, F.J.,Baxter, J.E.,Pike, A.C.W.,Nott, T.J.,Parkinson, D.-M.,Das, S.,Howell, S.,Fedorov, O.,Shen, Q.Y.,Fry, A.M.,Knapp, S.,Smerdon, S.J. Structure and Regulation of the Human Nek2 Centrosomal Kinase J.Biol.Chem., 282:6833-, 2007 Cited by PubMed: 17197699DOI: 10.1074/JBC.M609721200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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