2CJE
THE CRYSTAL STRUCTURE OF A COMPLEX OF Leishmania major DUTPASE WITH SUBSTRATE ANALOGUE DUPNHP
Summary for 2CJE
| Entry DOI | 10.2210/pdb2cje/pdb |
| Related | 2CIC 2YAY 2YAZ 2YB0 |
| Descriptor | DUTPASE, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
| Functional Keywords | pathogen, all-alpha, hydrolase, drug target |
| Biological source | LEISHMANIA MAJOR |
| Total number of polymer chains | 1 |
| Total formula weight | 30844.69 |
| Authors | Moroz, O.V.,Fogg, M.J.,Gonzalez-Pacanowska, D.,Wilson, K.S. (deposition date: 2006-03-31, release date: 2007-04-17, Last modification date: 2023-12-13) |
| Primary citation | Hemsworth, G.R.,Moroz, O.V.,Fogg, M.J.,Scott, B.,Bosch-Navarrete, C.,Gonzalez-Pacanowska, D.,Wilson, K.S. The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine. J.Biol.Chem., 286:16470-, 2011 Cited by PubMed: 21454646DOI: 10.1074/JBC.M111.224873 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.34 Å) |
Structure validation
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