2CJE

THE CRYSTAL STRUCTURE OF A COMPLEX OF Leishmania major DUTPASE WITH SUBSTRATE ANALOGUE DUPNHP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004170	molecular_function	dUTP diphosphatase activity
A	0005654	cellular_component	nucleoplasm
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 1267

Chain	Residue
A	GLU48
A	GLU51
A	DUN1266
A	MG1268
A	HOH2015
A	HOH2016

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG A 1268

Chain	Residue
A	ASP79
A	DUN1266
A	MG1267
A	MG1269
A	HOH2086
A	GLU48
A	GLU51
A	GLU76

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG A 1269

Chain	Residue
A	GLU51
A	GLU76
A	MG1268
A	HOH2030
A	HOH2033
A	HOH2086
A	HOH2088

---

site_id	AC4
Number of Residues	27
Details	BINDING SITE FOR RESIDUE DUN A 1266

Chain	Residue
A	GLN21
A	LEU24
A	ASN25
A	ILE28
A	TRP41
A	GLU48
A	GLU51
A	LYS59
A	TRP60
A	TRP61
A	ASP79
A	HIS82
A	PHE83
A	LYS179
A	ASN183
A	ARG186
A	TYR191
A	LYS198
A	ASN206
A	MG1267
A	MG1268
A	HOH2015
A	HOH2016
A	HOH2069
A	HOH2086
A	HOH2087
A	HOH2088

---