2CBX

X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from Streptomyces cattleya complexed with beta-D-erythrofuranosyl- adenosine

Summary for 2CBX

Entry DOI	10.2210/pdb2cbx/pdb
Related	1RQP 1RQR 2C2W 2C4T 2C4U 2C5B 2C5H
Descriptor	5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, BETA-D-ERYTHROFURANOSYL-ADENOSINE, GLYCEROL, ... (4 entities in total)
Functional Keywords	transferase, fluorinase, 5'-fluorodeoxyadenosine synthase, fla, inhibitor, aza, streptomyces cattleya, sam analogue
Biological source	STREPTOMYCES CATTLEYA
Total number of polymer chains	3
Total formula weight	98744.96
Authors	McEwan, A.R.,Cadicamo, C.D.,Deng, H.,McGlinchey, R.P.,Robinson, D.R.,O'Hagan, D.,Naismith, J.H.,Spencer, J. (deposition date: 2006-01-09, release date: 2007-03-06, Last modification date: 2023-12-13)
Primary citation	Cobb, S.L.,Deng, H.,McEwan, A.R.,Naismith, J.H.,O'Hagan, D.,Robinson, D.A. Substrate specificity in enzymatic fluorination. The fluorinase from Streptomyces cattleya accepts 2'-deoxyadenosine substrates. Org. Biomol. Chem., 4:1458-1460, 2006 Cited by PubMed: 16604208 DOI: 10.1039/b600574h PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation