2C97
LUMAZINE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO 4-(6- chloro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)butyl phosphate
Summary for 2C97
Entry DOI | 10.2210/pdb2c97/pdb |
Related | 1W19 1W29 2C92 2C94 2C9B 2C9D |
Descriptor | 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE, 4-(6-CHLORO-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL) BUTYL PHOSPHATE, POTASSIUM ION, ... (7 entities in total) |
Functional Keywords | transferase, riboflavin biosynthesis, inhibitor binding |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 5 |
Total formula weight | 85212.95 |
Authors | Morgunova, E.,Illarionov, B.,Jin, G.,Haase, I.,Fischer, M.,Cushman, M.,Bacher, A.,Ladenstein, R. (deposition date: 2005-12-09, release date: 2006-12-13, Last modification date: 2023-12-13) |
Primary citation | Morgunova, E.,Illarionov, B.,Sambaiah, T.,Haase, I.,Bacher, A.,Cushman, M.,Fischer, M.,Ladenstein, R. Structural and Thermodynamic Insights Into the Binding Mode of Five Novel Inhibitors of Lumazine Synthase from Mycobacterium Tuberculosis. FEBS J., 273:4790-, 2006 Cited by PubMed: 16984393DOI: 10.1111/J.1742-4658.2006.05481.X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report