2C78
EF-Tu complexed with a GTP analog and the antibiotic pulvomycin
Summary for 2C78
Entry DOI | 10.2210/pdb2c78/pdb |
Related | 1HA3 |
Descriptor | ELONGATION FACTOR TU-A, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase, gtpase, translation elongation factor, protein synthesis, antibiotic, gtp-binding, nucleotide-binding, phosphorylation, protein biosynthesis, elongation factor |
Biological source | THERMUS THERMOPHILUS |
Total number of polymer chains | 1 |
Total formula weight | 46067.36 |
Authors | Parmeggiani, A.,Krab, I.M.,Okamura, S.,Nielsen, R.C.,Nyborg, J.,Nissen, P. (deposition date: 2005-11-18, release date: 2006-03-16, Last modification date: 2023-12-13) |
Primary citation | Parmeggiani, A.,Krab, I.M.,Okamura, S.,Nielsen, R.C.,Nyborg, J.,Nissen, P. Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu. Biochemistry, 45:6846-6857, 2006 Cited by PubMed: 16734421DOI: 10.1021/bi0525122 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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