2C36

Structure of unliganded HSV gD reveals a mechanism for receptor- mediated activation of virus entry

2C36 の概要

• エントリーDOI: 10.2210/pdb2c36/pdb
• 関連するPDBエントリー: 1JMA 1L2G 2C3A
• 分子名称: GLYCOPROTEIN D HSV-1, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: virus, viral protein, herpes, immunoglobulin-like, glycoprotein, transmembrane
• 由来する生物種: HUMAN HERPESVIRUS 1 (HERPES SIMPLEX VIRUS (HSV-1, HUMAN))
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 65049.04

構造登録者

Krummenacher, C.,Supekar, V.M.,Whitbeck, J.C.,Lazear, E.,Connolly, S.A.,Eisenberg, R.J.,Cohen, G.H.,Wiley, D.C.,Carfi, A. (登録日: 2005-10-04, 公開日: 2005-11-23, 最終更新日: 2023-12-13)

• 主引用文献: Krummenacher, C.,Supekar, V.M.,Whitbeck, J.C.,Lazear, E.,Connolly, S.A.,Eisenberg, R.J.,Cohen, G.H.,Wiley, D.C.,Carfi, A.; Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry.; EMBO J., 24:4144-4153, 2005; PubMed: 16292345; DOI: 10.1038/sj.emboj.7600875

実験手法

X-RAY DIFFRACTION (2.11 Å)