2C36
Structure of unliganded HSV gD reveals a mechanism for receptor- mediated activation of virus entry
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | GLYCOPROTEIN D HSV-1 | polymer | 285 | 31558.8 | 2 | UniProt (P57083) Pfam (PF01537) In PDB | HUMAN HERPESVIRUS 1 (HERPES SIMPLEX VIRUS (HSV-1 HUMAN)) | |
| 2 | C, E | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G62182OO) | |||
| 3 | D | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 6 | water | water | 18.0 | 509 | Chemie (HOH) |
Sequence modifications
A, B: 23 - 307 (UniProt: P57083)
| PDB | External Database | Details |
|---|---|---|
| Cys 307 | His 332 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63117.6 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1759.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 171.8 | |
| All* | Total formula weight | 65049.0 |
