2C05
Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A
Summary for 2C05
Entry DOI | 10.2210/pdb2c05/pdb |
Related | 1GQV 1HI2 1HI3 1HI4 1HI5 1K2A 2BEX 2BZZ 2C01 2C02 |
Descriptor | NONSECRETORY RIBONUCLEASE, ACETIC ACID, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, ... (4 entities in total) |
Functional Keywords | endonuclease, eosinophil, hydrolase, nuclease, ribonuclease, rnase us, rnase-2, inhibitor, 5'-atp, ap3a, ap4a, ap5a, chemotaxis, glycoprotein, polymorphism, sensory transduction |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Lysosome (Probable): P10153 |
Total number of polymer chains | 1 |
Total formula weight | 16508.19 |
Authors | Baker, M.D.,Holloway, D.E.,Swaminathan, G.J.,Acharya, K.R. (deposition date: 2005-08-25, release date: 2006-01-18, Last modification date: 2023-12-13) |
Primary citation | Baker, M.D.,Holloway, D.E.,Swaminathan, G.J.,Acharya, K.R. Crystal Structures of Eosinophil-Derived Neurotoxin (Edn) in Complex with the Inhibitors 5'- ATP, Ap(3)A, Ap(4)A, and Ap(5)A. Biochemistry, 45:416-, 2006 Cited by PubMed: 16401072DOI: 10.1021/BI0518592 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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