2BZG

Crystal structure of thiopurine S-methyltransferase.

Summary for 2BZG

Entry DOI	10.2210/pdb2bzg/pdb
Descriptor	THIOPURINE S-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	methyltransferase, polymorphism, transferase, psi, protein structure initiative, structural genomics consortium (sgc)
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	27454.09
Authors	Battaile, K.P.,Wu, H.,Zeng, H.,Loppnau, P.,Dong, A.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Plotnikov, A.N.,Structural Genomics Consortium (SGC) (deposition date: 2005-08-17, release date: 2005-08-25, Last modification date: 2019-05-15)
Primary citation	Wu, H.,Horton, J.R.,Battaile, K.P.,Allali-Hassani, A.,Martin, F.,Zeng, H.,Loppnau, P.,Vedadi, M.,Bochkarev, A.,Plotnikov, A.N.,Cheng, X. Structural Basis of Allele Variation of Human Thiopurine-S-Methyltransferase. Proteins, 67:198-, 2007 Cited by PubMed: 17243178 DOI: 10.1002/PROT.21272 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation