Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
A | 0006805 | biological_process | xenobiotic metabolic process |
A | 0008119 | molecular_function | thiopurine S-methyltransferase activity |
A | 0008168 | molecular_function | methyltransferase activity |
A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
A | 0016740 | molecular_function | transferase activity |
A | 0032259 | biological_process | methylation |
A | 0042178 | biological_process | xenobiotic catabolic process |
A | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE SAH A1246 |
Chain | Residue |
A | LEU26 |
A | SER134 |
A | ILE135 |
A | ARG152 |
A | GLY153 |
A | HOH2036 |
A | HOH2068 |
A | HOH2223 |
A | HOH2224 |
A | HOH2225 |
A | TRP29 |
A | TRP33 |
A | PHE40 |
A | LEU69 |
A | CYS70 |
A | GLU90 |
A | ILE91 |
A | CYS133 |
site_id | AC2 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE B3P A1247 |
Chain | Residue |
A | ARG64 |
A | PRO111 |
A | ILE112 |
A | THR113 |
A | GLU114 |
A | TYR131 |
A | THR141 |
A | ASN142 |
A | ILE143 |
A | SER229 |
A | HOH2109 |
A | HOH2226 |
A | HOH2227 |
A | HOH2228 |
A | HOH2229 |
A | HOH2230 |
A | HOH2231 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 5 |
Details | BINDING: |
Chain | Residue | Details |
A | LEU69 | |
A | GLU90 | |
A | SER134 | |
A | ARG152 | |
A | TRP29 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | PHE40 | |
Chain | Residue | Details |
A | GLY14 | |
Chain | Residue | Details |
A | LYS58 | |