2BV5
CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 AT 1.8A RESOLUTION
Summary for 2BV5
Entry DOI | 10.2210/pdb2bv5/pdb |
Related | 2BIJ 2CJZ |
Descriptor | TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 5, SULFATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | ptpn5, step, phosphatase, hydrolase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 32714.10 |
Authors | Debreczeni, J.E.,Barr, A.J.,Eswaran, J.,Smee, C.,Burgess, N.,Gileadi, O.,von Delft, F.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Knapp, S. (deposition date: 2005-06-22, release date: 2005-07-14, Last modification date: 2023-12-13) |
Primary citation | Eswaran, J.,von Kries, J.P.,Marsden, B.,Longman, E.,Debreczeni, J.E.,Ugochukwu, E.,Turnbull, A.,Lee, W.H.,Knapp, S.,Barr, A.J. Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem. J., 395:483-491, 2006 Cited by PubMed: 16441242DOI: 10.1042/BJ20051931 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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