2BV5
CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 AT 1.8A RESOLUTION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 5 | polymer | 282 | 32525.9 | 1 | UniProt (P54829) Pfam (PF00102) | HOMO SAPIENS (HUMAN) | HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
A: 256 - 537 (UniProt: P54829)
| PDB | External Database | Details |
|---|---|---|
| Pro 257 | Ala 257 | engineered mutation |
| Asp 289 | Val 289 | variant |
| Leu 298 | Arg 298 | variant |
| Val 299 | Cys 299 | variant |
| Thr 517 | His 517 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32525.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 188.2 | |
| All* | Total formula weight | 32714.1 |
