2BU8

crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands

Summary for 2BU8

Entry DOI	10.2210/pdb2bu8/pdb
Related	2BTZ 2BU2 2BU5 2BU6 2BU7
Descriptor	PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	transferase, pyruvate dehydrogenase kinase 2 ghkl motif regulation
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	45228.18
Authors	Knoechel, T.R.,Tucker, A.D.,Robinson, C.M.,Phillips, C.,Taylor, W.,Bungay, P.J.,Kasten, S.A.,Roche, T.E.,Brown, D.G. (deposition date: 2005-06-08, release date: 2006-02-02, Last modification date: 2023-12-13)
Primary citation	Knoechel, T.R.,Tucker, A.D.,Robinson, C.M.,Phillips, C.,Taylor, W.,Bungay, P.J.,Kasten, S.A.,Roche, T.E.,Brown, D.G. Regulatory Roles of the N-Terminal Domain Based on Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands. Biochemistry, 45:402-, 2006 Cited by PubMed: 16401071 DOI: 10.1021/BI051402S PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation