2BRP
Crystal structure of S. pneumoniae hyaluronate lyase in complex with W249b
Summary for 2BRP
Entry DOI | 10.2210/pdb2brp/pdb |
Related | 1C82 1EGU 1F9G 1LOH 1LXK 1N7N 1N7O 1N7P 1N7Q 1N7R 1OJM 1OJN 1OJO 1OJP 1W3Y 2BRV 2BRW |
Descriptor | HYALURONATE LYASE, SULFAMIC ACID 1-DECYL-2-(4-SULFAMOYLOXYPHENYL)-1H-INDOL-6-YL ESTER, D-xylose, ... (5 entities in total) |
Functional Keywords | (alfa5/alfa5) barrel, lyase, peptidoglycan-anchor |
Biological source | STREPTOCOCCUS PNEUMONIAE |
Total number of polymer chains | 1 |
Total formula weight | 85016.31 |
Authors | Rigden, D.J.,Jedrzejas, M.J. (deposition date: 2005-05-10, release date: 2006-04-24, Last modification date: 2023-12-13) |
Primary citation | Rigden, D.J.,Botzki, A.,Nukui, M.,Mewbourne, R.B.,Lamani, E.,Braun, S.,von Angerer, E.,Bernhardt, G.,Dove, S.,Buschauer, A.,Jedrzejas, M.J. Design of new benzoxazole-2-thione-derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole. Glycobiology, 16:757-765, 2006 Cited by PubMed: 16638841DOI: 10.1093/glycob/cwj116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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