2BQV

HIV-1 protease in complex with inhibitor AHA455

Summary for 2BQV

Entry DOI	10.2210/pdb2bqv/pdb
Related	1HVC 2BB9
Descriptor	HIV-1 PROTEASE, 6-AMINO HEXANOIC ACID (3 entities in total)
Functional Keywords	hydrolase/inhibitor, hydrolase-inhibitor complex, hiv-1 protease, inhibitor, drug design, hydrolase complex
Biological source	HUMAN IMMUNODEFICIENCY VIRUS 1
Total number of polymer chains	2
Total formula weight	22196.21
Authors	Unge, T.,Ekegren, J.K.,Schenk, H.V.,Zreik Safa, M.,Wallberg, H.,Samuelsson, B.,Hallberg, A. (deposition date: 2005-04-28, release date: 2005-12-14, Last modification date: 2023-12-13)
Primary citation	Ekegren, J.K.,Unge, T.,Safa, M.Z.,Wallberg, H.,Samuelsson, B.,Hallberg, A. A New Class of HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimicking Scaffold. J.Med.Chem., 48:8098-, 2005 Cited by PubMed: 16335934 DOI: 10.1021/JM050790T PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation