2BJS
Isopenicillin N synthase C-terminal truncation mutant
Summary for 2BJS
Entry DOI | 10.2210/pdb2bjs/pdb |
Related | 1BK0 1BLZ 1HB1 1HB2 1HB3 1HB4 1IPS 1OBN 1OC1 1ODM 1ODN 1QIQ 1QJE 1QJF 1UZW 1W03 1W04 1W05 1W06 1W3V 1W3X 2BU9 |
Descriptor | ISOPENICILLIN N SYNTHETASE, FE (III) ION, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, ... (6 entities in total) |
Functional Keywords | oxidoreductase, antibiotic biosynthesis, b-lactam antibiotic, iron, oxygenase, penicillin biosynthesis, vitamin c |
Biological source | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
Total number of polymer chains | 1 |
Total formula weight | 37847.04 |
Authors | McNeill, L.A.,Sami, M.,Clifton, I.J.,Burzlaff, N.I. (deposition date: 2005-02-07, release date: 2006-03-09, Last modification date: 2024-05-08) |
Primary citation | McNeill, L.A.,Brown, T.J.N.,Sami, M.,Clifton, I.J.,Burzlaff, N.I.,Claridge, T.D.W.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J.,Schofield, C.J. Terminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non-Heme Iron Oxidases. Chemistry, 23:12815-12824, 2017 Cited by PubMed: 28703303DOI: 10.1002/chem.201701592 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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