2BIJ

Crystal structure of the human protein tyrosine phosphatase PTPN5 (STEP, striatum enriched enriched Phosphatase)

2BIJ の概要

• エントリーDOI: 10.2210/pdb2bij/pdb
• 分子名称: TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 5, SULFATE ION (3 entities in total)
• 機能のキーワード: ptpn5, step, phosphatase, hydrolase
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35300.91

構造登録者

Barr, A.J.,Debreczeni, J.E.,Eswaran, J.,Smee, C.,Burgess, N.,Gileadi, O.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Knapp, S.,von Delft, F. (登録日: 2005-01-21, 公開日: 2005-03-17, 最終更新日: 2023-12-13)

• 主引用文献: Eswaran, J.,von Kries, J.P.,Marsden, B.,Longman, E.,Debreczeni, J.E.,Ugochukwu, E.,Turnbull, A.,Lee, W.H.,Knapp, S.,Barr, A.J.; Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases.; Biochem. J., 395:483-491, 2006; PubMed: 16441242; DOI: 10.1042/BJ20051931

実験手法

X-RAY DIFFRACTION (2.05 Å)