2BEH
Crystal structure of antithrombin variant S137A/V317C/T401C with plasma latent antithrombin
Summary for 2BEH
Entry DOI | 10.2210/pdb2beh/pdb |
Related | 1T1F 1TB6 2B5T |
Descriptor | Antithrombin-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | antithrombin dimer, blood clotting |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P01008 P01008 |
Total number of polymer chains | 2 |
Total formula weight | 100161.94 |
Authors | Johnson, D.J.,Luis, S.A.,Huntington, J.A. (deposition date: 2005-10-24, release date: 2005-11-01, Last modification date: 2021-10-20) |
Primary citation | Johnson, D.J.,Langdown, J.,Li, W.,Luis, S.A.,Baglin, T.P.,Huntington, J.A. Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation. J.Biol.Chem., 281:35478-35486, 2006 Cited by PubMed: 16973611DOI: 10.1074/jbc.M607204200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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